Archives 2006

These seminars occured in the past.

Date	Speaker	Seminar Title	Host	Abstract
10-02-2006	David Holden Imperial College London, UK	The best of both worlds: interactions between Salmonella and the endocytic and secretory pathways	Bernd  Helms [(0)30 253 5375]
24-02-2006	Sven-Olof Olofsson Goteborg University, Goteborg, Sweden	The assembly of VLDL and the sorting of triglycerides between storage and secretion	Koert  Burger [(0)30 253 3477]	The assembly of VLDL starts with the biosynthesis of apoB-100 on ribosomes attached to the surface of the endoplasmic reticulum. The “nascent” apoB polypeptide is translocated to t ... read more
24-03-2006	Pete Cullen University Walk, Bristol, UK	Sorting nexins – diverse regulators of endosomal sorting and signalling.	Judith  Klumperman [(0)88 755 6650]	Sorting nexins – diverse regulators of endosomal sorting and signalling. Peter J. Cullen. The Henry Wellcome Integrated Signalling Laboratories, Department of Biochemistry, S ... read more
28-03-2006	Dan Cutler MRC, London, UK	Formation and function of Weibel-Palade Bodies; organelles at the interface of inflammation and haem	Gerrit van Meer [(0)30 253 3427]	Lui-Roberts, W.W., L.M. Collinson, L.J. Hewlett, G. Michaux, and D.F. Cutler. 2005. An AP-1/clathrin coat plays a novel and essential role in forming the Weibel-Palade bodies of en ... read more
31-03-2006	Declan Doyle University of Oxford, UK	Structural changes involved in Kir channel opening and closing	Antoinette  Killian [(0)30 253 3442]	Structural changes involved in Kir channel opening and closing Declan Doyle The combination of two processes define the function of any ion channel: selectivity and gating. Th ... read more
07-04-2006	Matthias Seedorf University of Heidelberg, Germany	A novel sorting pathway for an integral membrane protein to the yeast plasma membrane unusual time	Catherine  Rabouille [(0)88 755 9280]	Transport and local translation of mRNAs is an important step of the posttranscriptional regulation of gene expression. IST2 mRNA in yeast, which encodes an integral membrane prot ... read more
13-04-2006	Dmitry Veprintsev Medical Research Council Centre, Cambridge, UK	Core domain interactions in full length p53 in solution Unusual time	Stefan  Rüdiger [(0)30 253 3394]	The tumor suppressor p53 consists of four 393-residue chains, each of which has two natively unfolded (N- and C-terminal) and two folded (core and tetramerization) domains. The ... read more
21-04-2006	Ronald P. Kühnlein MPI, Goettingen, Germany	Fat flies - lipid storage control in Drosophila	Koert  Burger [(0)30 253 3477]	Tightly regulated reversible accumulation of fat stores is a universal strategy of organisms to survive life periods of paucity. From yeast to man storage fats (mainly triacylglyce ... read more
04-05-2006	Zvulun Elazar The Weizmann Institute of Science, Israel	Redox regulation of autophagy unusual time	Bernd  Helms [(0)30 253 5375]	Autophagy is a major catabolic pathway by which eukaryotic cells degrade and recycle excess or defective macromolecules and organelles. This pathway is activated under environmenta ... read more
12-05-2006	Bernhard Dobberstein University of Heidelberg, Germany	Signal sequences: More than just greasy peptides	Catherine  Rabouille [(0)88 755 9280]	Bernhard Dobberstein Signal sequences target ribosome-nascent-chain complexes to the membrane of the endoplasmic reticulum (ER) and mediate membrane insertion of secretory and m ... read more