Archives 2010

These seminars occured in the past.

Date	Speaker	Seminar Title	Host	Abstract
05-01-2010	Edgar Kooijman Department of Biological Sciences, Kent State University, Kent, USA	Biophysical endeavors into lipid phosphomonoester mediated signaling; The polyphosphoinositides and ceramide-1-phosphate	Antoinette  Killian [(0)30 253 3442]	The phosphorylated forms of phosphatidylinositol (PIPs), among all minor membrane lipid species, are arguably the most important in the regulation of intracellular signaling proces ... read more
11-01-2010	Ana Maria Cuervo Dept. of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, USA	Selective Autophagy: cleaning and fueling old cells	Fulvio  Reggiori [(0)88 755 6551]	Autophagy is the intracellular process that mediates the digestion of cellular components in lysosomes. The autophagic system fulfills two major functions in mammalian cells, servi ... read more
21-01-2010	Patrick Williamson Amherst College, USA	Sinking the life raft: Apoptosis and Plasma Membrane Structure	Joost  Holthuis [(0)30 253 6630]	pending
19-02-2010	Michael Schwake Unit of Molecular Cell Biology and Transgenic Research, Christian Albrechts University Kiel, Germany	New insights into the lysosomal transport of ß-glucocerebrosidase	Judith  Klumperman [(0)88 755 6650]	Recent Key publications: Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand beta-gluco ... read more
16-03-2010	Antonio Moschetta Laboratory of Lipid Metabolism and Cancer, University of Bari, Italy	Intestinal Specific Activation of Nuclear Receptor LXR Stimulates Reverse Cholesterol Transport and Protects from Atherosclerosis	Bernd  Helms [(0)30 253 5375]	Several steps of the HDL-mediated reverse cholesterol transport (RCT) are transcriptionally regulated by the nuclear receptors LXRs in the macrophages, liver and intestine. Systemi ... read more
23-03-2010	Richard Lehner Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, Canada	Role of Carboxylesterase3/Triacylglycerol Hydrolase in Lipid Metabolism	Martin  Houweling [(0)30 253 5379]	Excessive accumulation of triacylglycerol in peripheral tissues is tightly associated with obesity, and has been identified as an independent risk factor for insulin resistance, ty ... read more
26-03-2010	Miguel Penalva Centro de Investigaciones Biológicas CSIC, Madrid, Spain	Endocytic and secretory membrane traffic during persistent apical extension in Aspergillus nidulans	Fulvio  Reggiori [(0)88 755 6551]
16-04-2010	Jeroen van de Water Molecular Neurotherapy and Imaging Laboratory, Harvard Medical School, Boston USA	Stem cell-delivered immunotherapy for glioblastoma: The potential of anti-EGFR nanobodies and their variants	Paul van Bergen en Henegouwen [(0)30 253 3349]	Abstract Specifically targeted therapeutic agents combined with innovative modes of delivery, non-invasive imaging of drug delivery and efficacy are crucial in develop ... read more
23-04-2010	Stefan Höning Institute of Biochemistry, University of Koln	PtdIns4,5P2 is a key regulator for membrane recruitment and cargo binding of the AP2 clathrin adaptor complex	Rob  Mesman [(0)30 253 3477]	The AP2 adaptor complex (222 subunits) crosslinks the endocytic clathrin scaffold to PtdIns4,5P2-containing membranes and tr ... read more
21-05-2010	Hesso Farhan Biozentrum, University of Basel, Switzerland.	Regulation of architecture and function of the secretory pathway by signal transduction	Catherine  Rabouille [(0)88 755 9280]	To what extent the secretory pathway is regulated by cellular signaling is unknown. Here, we used RNA interference to explore the function of human kinase ... read more