Seminars 2008

Date Speaker Seminar Title Host Abstract
18-04-2008 Liesbeth Veenhof
Department of Biochemistry, University of Groningen
The nuclear envelope as a dynamic border Fulvio  Reggiori
[(0)88 755 6551]
Carrying Precious Cargo:

The nuclear envelope as a dynamic border

The nucleus harbors what is arguably the most precious cargo of cells: the genetic mater … read more

09-05-2008 Elke Deuerling
Molecular Microbiology, Department of Biology, University of Konstanz, Germany
Getting Proteins into Shape: Insights into the Functions and Mechanisms of Molecular Chaperones Stefan  Rüdiger
[(0)30 253 3394]
22-05-2008 Jesus Salgado
Department of Medicinal Chemistry, University of Valencia, Spain
Orientation of membrane peptides: A view from dynamics Antoinette  Killian
[(0)30 253 3442]
Biological membranes are partially ordered and highly mobile supramolecular complexes, in which the constituent lipids and proteins (or peptides) are intrinsically dynamic. Because … read more
10-06-2008 Javier Sancho
Dept. Biochemsitry and Molecular and Cellular Biology, University of Zaragoza, Zaragoza, Spain
Functional and defective human LDL receptor: insights on LDL uptake and on familial hypercholesterolemia Cees  Rodenburg
[(0)30 253 9331]
Cholesterol travelling in plasma in LDL particles is internalized by the LDL receptor (LDLR). Defective mutants of LDLR give rise to Familial Hypercholesterolemia, a disease affec … read more
20-06-2008 Mikael Simons
Max-Planck Institute for Experimental Medicine, Göttingen, Germany
Exosome biogenesis in oligodendrocytes Sylvia  Neumann
[(0)30 253 3966]
Exosomes are small vesicles with a diameter of approximately 50-100 nm that are secreted by a number of different cells. Exosomes are thought to derive from intraluminal vesicles o … read more
01-07-2008 Mike Koomey
Department of Molecular Biosciences, University of Oslo, Norway
Protein glycosylation in Neisseria gonorrhoeae – a human pathogen shows its sweet side Jan  Tommassen
[(0)30 253 2999]
07-07-2008 Jagath Reddy Junutula
Genentech Inc., 1 DNA Way, South San Francisco, USA
Targeted Cancer Chemotherapy: New Insights into Antibody Drug Conjugates Ann de Mazière
[(0)88 755 6551]
Conventional antibody-drug conjugation strategies yield heterogeneous conjugates that are active on target cells but also produce systemic toxicities. In an effort to generate anti … read more
01-10-2008 Wolfgang Loffelhardt
Max F. Perutz Laboratories, University of Vienna, Austria
Protein targeting into and within a primitive plastid, the cyanelle of Cyanophora paradoxa Hans de Cock
[(0)30 253 6616]
Host will be Sjef Smeekens (030-253 3431)
07-11-2008 Matthias Mayer
Zentrum fuer Molekulare Biologie Heidelberg, Heidelberg University, Germany
Conformational Dynamics of the Hsp90 chaperone machine Stefan  Rüdiger
[(0)30 253 3394]
The highly conserved Hsp90 chaperones use ATP to regulate stability and activity of many signaling molecules like protein kinases and transcription factors. Crystallographic and el … read more
02-12-2008 Hidde Ploegh
MIT, Boston, USA
Protein surgery and mouse engineering: new tools for cell biology and immunology Madelon  Maurice
[(0)88 755 7574]
15-12-2008 Tim Levine
Department of Cell Biology, University College London, Institute of Ophthalmology te Londen, UK
A role for PI(4,5)P2 5-phosphatase OCRL1 in polarised epithelia Gerrit van Meer
[(0)30 253 3427]
Posted in Seminars archive