| Date | Speaker | Seminar Title | Host | Abstract |
| 11-01-2010 | Ana Maria Cuervo Dept. of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, USA |
Selective Autophagy: cleaning and fueling old cells | Fulvio Reggiori [(0)88 755 6551] |
Autophagy is the intracellular process that mediates the digestion of cellular components in lysosomes. The autophagic system fulfills two major functions in mammalian cells, servi … read more |
| 21-01-2010 | Patrick Williamson Amherst College, USA |
Sinking the life raft: Apoptosis and Plasma Membrane Structure | Joost Holthuis [(0)30 253 6630] |
pending |
| 19-02-2010 | Michael Schwake Unit of Molecular Cell Biology and Transgenic Research, Christian Albrechts University Kiel, Germany |
New insights into the lysosomal transport of ß-glucocerebrosidase | Judith Klumperman [(0)88 755 6650] |
Recent Key publications:
Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand beta-gluco … read more |
| 16-03-2010 | Antonio Moschetta Laboratory of Lipid Metabolism and Cancer, University of Bari, Italy |
Intestinal Specific Activation of Nuclear Receptor LXR Stimulates Reverse Cholesterol Transport and Protects from Atherosclerosis | Bernd Helms [(0)30 253 5375] |
Several steps of the HDL-mediated reverse cholesterol transport (RCT) are transcriptionally regulated by the nuclear receptors LXRs in the macrophages, liver and intestine. Systemi … read more |
| 26-03-2010 | Miguel Penalva Centro de Investigaciones Biológicas CSIC, Madrid, Spain |
Endocytic and secretory membrane traffic during persistent apical extension in Aspergillus nidulans | Fulvio Reggiori [(0)88 755 6551] |
|
| 16-04-2010 | Jeroen van de Water Molecular Neurotherapy and Imaging Laboratory, Harvard Medical School, Boston USA |
Stem cell-delivered immunotherapy for glioblastoma: The potential of anti-EGFR nanobodies and their variants | Paul van Bergen en Henegouwen [(0)30 253 3349] |
Abstract
Specifically targeted therapeutic agents combined with innovative modes of delivery, non-invasive imaging of drug delivery and efficacy are crucial in develop … read more |
| 23-04-2010 | Stefan Höning Institute of Biochemistry, University of Koln |
PtdIns4,5P2 is a key regulator for membrane recruitment and cargo binding of the AP2 clathrin adaptor complex | Rob Mesman [(0)30 253 3477] |
The AP2 adaptor complex (222 subunits) crosslinks the endocytic clathrin scaffold to PtdIns4,5P2-containing membranes and tr … read more |
| 21-05-2010 | Hesso Farhan Biozentrum, University of Basel, Switzerland. |
Regulation of architecture and function of the secretory pathway by signal transduction | Catherine Rabouille [(0)30-2121 941] |
To what extent the secretory pathway is regulated by cellular signaling is unknown. Here, we used RNA interference to explore the function of human kinase … read more |
| 04-06-2010 | Jesse Hay Div. of Biological Sciences & Center for Structural and Functional Neuroscience, The U. of Montana |
Mechanisms of ER to Golgi Transport: Luminal Calcium, Vesicle Coats, SNAREs, and Neurodegeneration | Judith Klumperman [(0)88 755 6650] |
This IB seminar will describe the highlights of two projects investigating molecular mechanisms in ER-to-Golgi vesicle trafficking: 1) Potential roles of lumina … read more |
| 08-06-2010 | Bill Skach Division of Hematology and Medical Oncology, Oregon Health & Science University, USA |
Spectroscopic analysis of nascent protein folding on (and off) the ribosome | Ineke Braakman [(0)30 253 2759] |
|
| 11-06-2010 | Andreas Conzelmann University of Fribourg, Department of Medicine, Division of Biochemistry |
Biosynthesis, turnover and function of sphingolipids in the yeast Saccharomyces cerevisiae | Gerrit van Meer [(0)30 253 3427] |
In yeast inositolphosphorylceramides (IPCs) mostly contain C26:0 fatty acids and were considered to be important for viability, since the IPC synthase AUR1 is essential. lcb1∆ … read more |
| 18-06-2010 | Sebastian Springer Biochemistry and Cell Biology Jacobs University Bremen, Germany |
MHC class I: ligand binding, quality control, and ER-Golgi transport | Ineke Braakman [(0)30 253 2759] |
|
| 10-09-2010 | Satyajit Mayor National Centre for Biological Sciences, Bangalore, India; |
Gerrit van Meer [(0)30 253 3427] |
Active remodeling of cortical actin regulates spatiotemporal organization of cell surface molecules : a new paradigm for the construction of membrane domains in living cell membran … read more | |
| 15-09-2010 | Stuart Kornfeld Washington University School of Medicine, St. Louis, Missouri |
New insights into the Man-6-P lysosomal targeting system | Judith Klumperman [(0)88 755 6650] |
We are studying the biochemical and molecular basis for protein trafficking in mammalian cells, focusing on the biogenesis of lysosomes. The targeting of lysosomal enzymes from the … read more |
| 19-11-2010 | Cristina Risco National Research Counsel of Spain, CSIC, Madrid |
Studying virus factories and cell architecture with new high resolution imaging techniques | Raoul de Groot [(0)30 253 1463] |
Viruses are genetically simple associations of macromolecules that exhibit a variable complexity from a structural point of view. Complex, enveloped viruses, some of them important … read more |
| 26-11-2010 | Dimitrios Stamou Dept. of Neuroscience and Pharmacology, and Nano-Science Center, University of Copenhagen, Denmark |
Nanoscale membrane-curvature as an allosteric modulator of protein localization and function | Gerrit van Meer [(0)30 253 3427] |
To date we have established exhaustive correlations between the lipid composition of membranes and its impact on membrane properties and protein function. In addition to compositio … read more |
Seminars 2010
Posted in Seminars archive
